Steven T Pals Selected Research

B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)

1/2023	Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation.
1/2021	A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies.
10/2013	Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients.
3/2012	The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia.

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Steven T Pals Research Topics

Disease

18	Neoplasms (Cancer) 01/2023 - 02/2002
13	Multiple Myeloma 12/2021 - 02/2002
9	Lymphoma (Lymphomas) 02/2024 - 01/2003
7	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 09/2002
6	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 03/2024 - 01/2006
5	Waldenstrom Macroglobulinemia (Macroglobulinemia) 03/2024 - 03/2016
5	Inflammation (Inflammations) 01/2019 - 02/2002
5	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 03/2011 - 09/2002
4	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 03/2024 - 10/2013
4	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2023 - 03/2012
4	Leukemia 01/2022 - 09/2008
4	Carcinogenesis 12/2020 - 02/2002
3	Adenoma (Adenomas) 10/2017 - 09/2002
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2023 - 09/2006
2	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 11/2014 - 04/2005
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/2012 - 06/2010
2	Aberrant Crypt Foci 03/2011 - 05/2008
2	Atherosclerotic Plaque (Atheroma) 09/2010 - 10/2002
2	Burkitt Lymphoma (Burkitt's Lymphoma) 06/2010 - 06/2009
2	X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency) 01/2007 - 11/2003
2	Carcinoma (Carcinomatosis) 08/2006 - 09/2002
2	Fibrosis (Cirrhosis) 03/2006 - 02/2002
2	Chronic Renal Insufficiency 03/2006 - 02/2002
2	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2003 - 03/2002
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023
1	Weight Loss (Weight Reduction) 01/2022
1	Polyneuropathies (Polyneuropathy) 01/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2018
1	Hyperplasia 10/2013
1	Molluscum Contagiosum 10/2013
1	Shock 01/2013
1	Lymphadenopathy 03/2012
1	Lymphocytosis 03/2012
1	Bone Diseases (Bone Disease) 11/2011
1	Thrombosis (Thrombus) 09/2010
1	Colonic Neoplasms (Colon Cancer) 01/2010
1	Hematologic Neoplasms (Hematological Malignancy) 06/2009

Drug/Important Bio-Agent (IBA)

7	ibrutinibIBA 03/2024 - 03/2012
5	IntegrinsIBA 03/2024 - 01/2003
5	ChemokinesIBA 12/2021 - 01/2007
5	Syndecan-1 (Syndecan 1)IBA 01/2021 - 02/2002
5	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2020 - 02/2002
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2020 - 09/2002
4	Agammaglobulinaemia Tyrosine KinaseIBA 03/2024 - 03/2012
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2003
4	LigandsIBA 12/2020 - 12/2010
4	CateninsIBA 01/2019 - 03/2011
4	beta CateninIBA 09/2008 - 09/2002
3	B-Cell Antigen Receptors (B Cell Antigen Receptors)IBA 01/2022 - 04/2005
3	Immunoglobulin M (IgM)IBA 01/2022 - 03/2002
3	CytokinesIBA 01/2019 - 01/2013
3	Protein Isoforms (Isoforms)IBA 10/2017 - 03/2002
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2013 - 02/2002
3	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 05/2013 - 02/2002
3	AntigensIBA 05/2013 - 07/2002
3	Glycoproteins (Glycoprotein)IBA 03/2006 - 02/2002
2	ParaproteinsIBA 01/2022 - 01/2018
2	Heparitin Sulfate (Heparan Sulfate)IBA 12/2021 - 01/2010
2	Phosphotransferases (Kinase)IBA 01/2020 - 10/2017
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 09/2006
2	ErbB Receptors (EGF Receptor)IBA 10/2019 - 10/2017
2	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 01/2017 - 11/2014
2	Amino Acids FDA Link 01/2017 - 04/2005
2	Hyaluronic Acid (Hyaluronan)IBA 09/2010 - 03/2006
2	MicroRNAs (MicroRNA)IBA 06/2010 - 06/2009
2	TCF Transcription FactorsIBA 09/2008 - 09/2002
2	HGF activatorIBA 01/2006 - 10/2004
2	Immunoglobulins (Immunoglobulin)IBA 04/2005 - 01/2003
2	Immunoglobulin G (IgG)IBA 04/2005 - 03/2002
2	Immunoglobulin A (IgA)IBA 01/2003 - 02/2002
1	carboxyl radical (COO-)IBA 04/2024
1	acalabrutinibIBA 03/2024
1	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2024
1	Casein Kinase II (Casein Kinase 2)IBA 01/2023
1	venetoclaxIBA 01/2023
1	EnzymesIBA 01/2023
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2023
1	Proteasome InhibitorsIBA 01/2022
1	ixazomibIBA 01/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022
1	Rituximab (Mabthera)FDA Link 01/2022
1	Chemokine CXCL12IBA 12/2021
1	src-Family KinasesIBA 01/2021
1	Epidermal Growth Factor (EGF)IBA 10/2017
1	tyrosine receptor (receptor, tyrosine)IBA 10/2017
1	Proto-Oncogene Proteins c-metIBA 10/2017
1	RNA (Ribonucleic Acid)IBA 01/2017
1	idelalisibIBA 03/2016
1	Immunoglobulin E (IgE)IBA 10/2013
1	Fibronectins (Fibronectin)IBA 03/2012
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 03/2012
1	Cadherins (E-Cadherin)IBA 11/2011
1	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 09/2010
1	Matrix Metalloproteinases (MMPs)IBA 09/2010
1	CollagenIBA 09/2010
1	LipidsIBA 09/2010
1	EpitopesIBA 01/2010

Therapy/Procedure

8	Therapeutics 02/2024 - 10/2017
1	Precision Medicine 08/2015
1	Hematopoietic Stem Cell Transplantation 10/2013